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Tuberculosis POC

Safeguard Lives with ICHORtec’s Quantum Leap in TB Detection at POC

Figure 1: ICHORtec’s Quantum-Powered TB Point-of-Care Solution detects TB and Rifampicin Resistance in a single test
ICHORtec’s Quantum-Powered TB Point-of-Care Solution detects TB and Rifampicin Resistance in a single test

Rapid molecular TB screening with on-device resistance calling, built for programs that need speed, scale, and traceability.

The challenge

Tuberculosis (TB) claims over 1.6 million lives yearly, with drug-resistant strains like MDR-TB and XDR-TB spiking costs and spreading globally. Slow, centralized testing delays care and loses patients.

The solution

Target Mycobacterium tuberculosis and rifampicin resistance with precision, detecting the 81-base-pair rpoB region (codons 507-533) in under 3-5 minutes. Measure ΔG binding energy for single-nucleotide accuracy (e.g., S531L, H526Y, D516V), even in challenging samples. Closed cartridges ensure safety; UUID traceability links to cloud surveillance for outbreak alerts and stewardship.

 

What it measures

  • Target: 81-base-pair rpoB sequence (codons 507-533).
  • Mechanism: ΔG shift between probe and TB DNA.
  • Variants: Detects S531L, H526Y, D516V.
  • Results: TB positive/negative, rifampicin status, timestamp, UUID.

 

Figure 2: Measures the free binding energy (ΔG) — visualizing real-time differentiation of TB and rifampicin-resistant strains through the Q-FMB® hybridization method
Measures the free binding energy (ΔG) — visualizing real-time differentiation of TB and rifampicin-resistant strains through the Q-FMB® hybridization method

Core Benefits

  • Speed: Results in 5 minutes for swift triage.
  • Accuracy: 100% analytical precision in validations; ISO 13485/GCLP compliant.
  • Portability: Lab-free design for EDs, clinics, and wards.
  • Connectivity: Bluetooth exports, real-time dashboards for proactive control.

Why it matters

  • Treat patients in one visit, reducing drop-offs.
  • Speed triage in high-burden, remote areas.
  • Share anonymized data for resource planning.
  • Reveal TB and resistance via Q-FMB® hybridization.

Simple Workflow - Transformative Impact

Collect sputum sample, load into a FMB tube, insert into ICHORscope, and get “TB positive/negative” and rifampicin status with controls in minutes. Secure data flows to the cloud for analytics—enabling same-day treatment and HAI prevention. Importantly, UUID traceability links to cloud surveillance for outbreak alerts and stewardship.

Figure 3: Customer Journey with ICHORtec’s Q-FMB® TB POC Platform. Sample in. Quantum analysis. Automated result. Instant reporting. Same day decision.
Customer Journey with ICHORtec’s Q-FMB® TB POC Platform. Sample in. Quantum analysis. Automated result. Instant reporting. Same day decision.

Regulatory Status

The Q-FMB® – TB and ICHORscope platform are progressing through the regulatory pathway toward WHO prequalification and international diagnostic approval. ICHORtec is collaborating with leading global research centers to complete the clinical validation phase. During this period, Q-FMB® systems are available as Research Use Only (RUO) products under the ICHORtec Research Framework, aligned with ISO 13485 and GCLP standards.

Elevate your fight against TB. Precision meets urgency for safer care.

Request Research Use Only Product Now!